Empathy plays a significant role in the narrative, particularly in the interactions between the characters and Hannibal Lecter. Will Graham's empathy disorder allows him to understand and predict the thoughts and actions of serial killers, including Lecter, making him an invaluable profiler for the FBI. However, his empathy also puts him at risk, as he becomes vulnerable to Lecter's influence and manipulation. Lecter, on the other hand, is capable of both cognitive and emotional empathy, which he uses to understand others and manipulate them. This empathy is a double-edged sword; while it allows him to connect with others, it also enables him to exploit their vulnerabilities. The narrative explores the dangers of empathy, especially when it comes into contact with a character like Lecter, who uses it for his own gain and to further his own twisted philosophy.