This volume constitutes refereed proceedings of the 5th International Conference on Digital Transformation and Global Society, DTGS 2020, held in St. Petersburg, Russia, in June 2020. Due to the COVID-19 pandemic the conference was held online. The 30 revised full papers and 6 short papers presented in the volume were carefully reviewed and selected from 108 submissions. The papers are organized in topical sections on virtual communities and online activism; computational social science; governance and politics on the Internet; smart cities and urban governance; digital economy and consumer behavior; digital culture and education; international workshop " 4P-medicine & Digital Transformation".